IGA ANTIBODY INDUCED BY IMMUNIZATION WITH PNEUMOCOCCAL POLYSACCHARIDES IS A PROGNOSTIC TOOL IN COMMON VARIABLE IMMUNE DEFICIENCIES

IGA Antibody Induced by Immunization With Pneumococcal Polysaccharides Is a Prognostic Tool in Common Variable Immune Deficiencies

The evaluation of the response to vaccination in patients with inborn errors of immunity is a tool to evaluate T-dependent and T-independent antibody residual function of B lymphocytes and it is part of the diagnostic definition for Common Variable Immune Deficiencies.Currently used classifications for Common Variable Immune Deficiencies patients a

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Normalization of the tumor microenvironment by harnessing vascular and immune modulation to achieve enhanced cancer therapy

Abstract Solid tumors are complex entities that actively shape their microenvironment to create a supportive environment for their own growth.Angiogenesis and immune suppression are two key characteristics of this tumor microenvironment.Despite attempts to deplete tumor blood vessels using antiangiogenic drugs, extensive vessel pruning has shown li

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